This is the place where you can tell us about anything that you think we should cover. You can either mention a specific paper, or perhaps a field or topic that you think is of importance.
We are trying to limit ourself to open-access papers, since we know there are people who may like to participate but who do not have institutional access to paid-for journals. A list of open-access journals can be found here, though we’ve not tried it for accuracy, and there appear to be caveats e.g. papers becoming open-access after 6 months.
You can see which papers we’ve already looked at here.
Just add your ideas as a comment below…
Well done again ladies. Just throwing the broad topic of screening into the ring. Some lovely papers to look at ethics and how useful NNT (or rather NNS… nums needed to screen), positive predictive value and neg pred value can be in helping to make decisions about implementing programmes. I don’t have specific papers right now, but if you’re interested let me know and we can dig some out.
http://www.hms.harvard.edu/pallcare/Documents/Temel%20et%20al.pdf
Early palliative care in non-small cell lung cancer results in less aggressive treatement at end of life, and increased survival.
Having recently studied pre-emptive surgery and discussing the problems faced with management of potentially malignant lesions, I’ve particularly found the views of this paper extremely interesting, but worry about the ethical and emotional impact of their proposal to reclassify a skin condition as a carcinoma http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.2007.07860.x/abstract
Would love to discuss this paper with everyone.
http://www.cmaj.ca/cgi/content/abstract/cmaj.101668v1?ijkey=1390007ceb3742c0115a30ed7f8dc04ded2be566&keytype2=tf_ipsecsha
Use of ABCD2 being questioned. Widely used, NICE recommended.
Regards
Russell
@drbrown1970
Placebos without Deception: A Randomized Controlled
Trial in Irritable Bowel Syndrome
Ted J. Kaptchuk1,2*, Elizabeth Friedlander1, John M. Kelley3,4, M. Norma Sanchez1, Efi Kokkotou1,
Joyce P. Singer2, Magda Kowalczykowski1, Franklin G. Miller5, Irving Kirsch6, Anthony J. Lembo1
You’ve just done a critical care paper of course – but an important study in the NEJM showing harm with fluid resus in peadiatric sepsis. Lots to talk about here, but I would have thought you’ll want another speciality….
http://www.nejm.org/doi/full/10.1056/NEJMoa1101549?query=featured_home
I’ve made a few comments on it here..
http://criticalinsight.wordpress.com/2011/05/28/a-black-water-day/
Looks like you’ve hit on something here!
Dan
Hi.
Suggestion for discussion around the association between the infectious agent XMRV and chronic fatigue syndrome (CFS) (original 2009 article here: http://www.sciencemag.org/content/326/5952/585). This is now much-disputed (often heatedly) and there are two new articles pertaining to this, published in Science (http://www.sciencemag.org/content/early/2011/06/01/science.1205292 *** and *** http://www.sciencemag.org/content/early/2011/06/01/science.1204963) along with an ‘Editorial Expression of concern’ (http://www.sciencemag.org/content/early/2011/06/01/science.1208542.full.pdf).
I (an academic researcher) think this is all interesting stuff, but it also nicely bridges the gap into clinical medicine and the need for ongoing research into the causes of CFS.
Thanks
@NathanCroft
The original Science paper is a good example of what can go wrong when the most rigorous methodology is not applied. We raised some of these in a reply (http://www.ncbi.nlm.nih.gov/pubmed/20466906), but these failings of the first paper have been largely lost as the focus has shifted to the difficulties in replicating the findings in other studies.
So a good topic for a JC, but be wary of the potential that you might attract attention from some who consider that the application of rigorous science to the problem of CFS/ME is denying patients (who do of course experience substantial disability) potentially effective treatments. Of course, the application of rigorous scientific principles in fact defends them from quackery, but things aren’t always seen in that light. You’d need to be careful to ensure things didn’t descend into a series of rants. On the other hand, it’s never to late for anyone to learn …
[...] organizers choose a paper, which they announce at their website (you can make suggestions here or via a tweet). Ideally, people should read the entire paper before the Twitter session. A [...]
Just leaving a suggestion for a paper that has had a strong influence on current nephrology practice in the past 5 years, especially in the establishment of the ‘Fistula First’ mindset prominent in the USA and now becoming popular in European practice.
Type of Vascular Access and Survival among Incident Hemodialysis Patients: The Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study
Brad C. Astor, Joseph A. Eustace, Neil R. Powe, Michael J. Klag, Nancy E. Fink, Josef Coresh, and for the CHOICE Study JASN May 1, 2005 16: 1449-1455
A link to the paper is below and I’m happy to review for the journal club. http://bit.ly/ljZ4gE
Regards
Richard McCrory
@iamdoctord
[...] organizers select a paper, that they announce during their website (you can make suggestions here or around a tweet). Ideally, people should examination a whole paper before a Twitter session. A [...]
@themattmak has come up with two great paper suggestions via Twitter:
1. The CRASH-2 study which won the BMJ paper of the year this year
2. the paper on the WHO Safer Surgery checklist published in the NEJM
Thank you to all for the suggestions, can’t wait to discuss them all over the coming weeks!
Antidepressant efficacy meta-analysis. Shows two pretty clear winners. Both useful for primary care prescribing. Also, moe-importantly, shows which ADs are not efficacious or are downright harmful, which should help clear up a bit of dodgy primary care habit prescribing.
http://www.ncbi.nlm.nih.gov/pubmed/19185342
Think we should really only discuss open-access papers. It would be good to look at this as a topic and see how this paper can be rationalised with other meta-analyses eg Kirsch et al
Would love to discuss: Graduates of different UK medical schools show substantial differences in performance on MRCP(UK) Part 1, Part 2 and PACES examinations.
http://www.biomedcentral.com/1741-7015/6/5
Something a bit different and #Meded related, I’m sure it would promote some interesting debate.
@drdlittle
Here’s my reply to silv24
@silv24 http://tinyurl.com/6h6bef9 http://tinyurl.com/6e5efny http://tinyurl.com/5u7fd62 few suggestions @twitjournalclub all Sz I’m afraid
Another suggestion: it would be really great to invite someone along to present their own work. Should be easier to do on twitter than in person. Just have to decide on a suitable person and a suitable paper.
Thanks David. We also think that’d be really great, and have already got some idea about that in the pipeline!
Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study http://www.bmj.com/content/342/bmj.d2549.full
my suggestion: Prevention of nosocomial infection in cardiac surgery by decontamination of the nasopharynx and oropharynx with chlorhexidine gluconate: a randomized controlled trial. http://www.ncbi.nlm.nih.gov/pubmed/17119142
My suggestion:
The wizard and the gatekeeper: a fairytale
This is a classic paper that explores the relationship between primary and secondary care. Its also has great relevance to the recent NHS reforms.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1835499/
Is it too soon to go a bit meta and talk about a paper that discusses physicians’ use of social media?
Maybe something diabetes-related? I thought the recently published ‘T2 reversal’ paper was interesting as something which was too pilot-ish to draw many conclusions from, but which was much publicised in the media.
I blogged about the paper here, which is freely available from the links below: http://brodiesnotes.blogspot.com/2011/06/some-thoughts-on-recent-type-2-diabetes.html
Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC and Taylor R (2011) Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol Diabetologia
doi: 10.1007/s00125-011-2204-7
html: http://www.springerlink.com/content/68rmr50h7j024525/fulltext.html
pdf: http://www.springerlink.com/content/68rmr50h7j024525/fulltext.pdf
Palliative care paper suggestions:
Interesting paper here on dying patients perceptions of euthanasia http://pmj.sagepub.com/content/early/2011/05/04/0269216311404275.abstract
OR
Lots of papers here http://pmj.sagepub.com/content/current about the use of opioids in cancer pain, interesting to choose one to debate
OR
Neat little audit showing changes in preferences for place of death http://pmj.sagepub.com/content/25/4/333.abstract
Apologies for being journal centric. @palliativemedj
I’d like to suggest this paper:
http://www.biomedcentral.com/1741-7015/9/89/abstract
Can user testing of a clinical trial patient information sheet make it fit-for-purpose? – a randomised controlled trial
Peter Knapp , David K Raynor , Jonathan Silcock and Brian Parkinson
BMC Medicine 2011, 9:89doi:10.1186/1741-7015-9-89
Published: 21 July 2011
First off I would like to say excellent blog! I had a quick question in which
I’d like to ask if you don’t mind. I was curious to know how you center yourself
and clear your mind before writing. I have had a tough time clearing my thoughts in getting my ideas out.
I do enjoy writing however it just seems like the first 10 to
15 minutes tend to be lost just trying to figure out how to begin.
Any recommendations or hints? Appreciate it!
Your style is really unique in comparison to
other people I have read stuff from. Many thanks for posting when you have the
opportunity, Guess I will just book mark this page.